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Vasopressor and inotrope infusions

One rate, converted into every unit the drug is actually dosed in, beside the published ranges and the source each one comes from.

kg
Rate is stated in
mcg/min
Enter a weight and a rate to convert between every unit this drug is dosed in.
  • The FDA label and the heart failure guideline state this drug per minute; WFSA and the Surviving Sepsis Campaign state it per kilogram per minute. Both are published, and this calculator shows the rate in both units rather than choosing.
  • No authoritative maximum rate was found to cite, so none is shown.
  • The label states the rate is reduced gradually rather than stopped abruptly.

Whether a drug is dosed per minute or per kilogram per minute is a property of the SOURCE, not of the drug: norepinephrine is published both ways for an infusion. Each published range names the source that states it, and this patient's rate is shown in that source's own unit.

Formula

  • Dose per minute = rate (mL/hr) x concentration (per mL) / 60
  • Rate (mL/hr) = dose per minute x 60 / concentration (per mL)
  • Vasopressin is dosed in units per minute and angiotensin II in nanograms per kilogram per minute
  • Dose per kg per minute = dose per minute / weight (kg)

Source

  • FDA prescribing information for each agent (DailyMed, dailymed.nlm.nih.gov); 2022 AHA/ACC/HFSA heart failure guideline Table 20; WFSA Update in Anaesthesia; StatPearls. Each published range carries the source it came from.

Clinical reference only. Verify independently; clinical judgment governs.